"Mother" is the lead single from Blondie's ninth studio album Panic of Girls and was written by Kato Khandwala, Ben Phillips (Guitarist for The Pretty Reckless) and the band's lead singer Deborah Harry. It was released in the United Kingdom on May 22, 2011, on all major online platforms. It is the first single release from the band since "Good Boys" in 2003.

The song was first performed in 2010 along with several other tracks from Panic of Girls during the band's Australian tour, as well as during festival appearances in the UK.

On December 5, 2010, "Mother" was made available as a free download from the official Blondie website. The track was later remixed with a different vocal take for the album and single release. The track was played for the first time on March 17, 2011, on BBC Radio 2's The Ken Bruce Show. On Amazon.co.uk an explicit version was released alongside the regular one.

The cover artwork for "Mother" was revealed on May 5, 2011. It displays a band picture digitally manipulated to resemble a Chris Berens painting, like the artwork for its parent album. Elements of the Panic of Girls cover art are used. Also the text is inspired by the original writing by Berens.

The official music video was directed by Laurent Rejto and features cameos by Kate Pierson from The B-52's, James Lorinz (Frankenhooker), Johnny Dynell, Chi-Chi Valenti, The Dazzle Dancers, Rob Roth, Barbara Sicuranza, Larry Fessenden, Alan Midgette (Andy’s double), The Five Points Band, Guy Furrow, Kitty Boots and Hattie Hathaway. It was released on May 17, 2011, on the YouTube channel of Blondie's record label, Five Seven Music.

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