Mor Ní Briain was Queen of Connacht, and died 1218. She was a daughter of King Domnall Mór Ua Briain of Thomond (died 1194). Domnall's wife was Órlaith Ní Murchadha, Princess of Leinster, daughter of Queen Mor Ui Thuathail and King Diarmaid Mac Murchadha of Leinster.
Mór's siblings included:
She was a niece of Aoife of Leinster, a first cousin to both Isabel de Clare, 4th Countess of Pembroke and Richard Mór de Burgh. Relatives included Archbishop Lorcán Ua Tuathail, Cormac mac Art O Melaghlain, Brian Ua Néill, Ruadhri Ua Flaithbertaigh, and William Marshal, 2nd Earl of Pembroke.
Her ancestors included High King of Ireland Brian Boru (died 1014), King Énnae Cennsalach of Leinster (fl. 5th century), Bé Binn inion Urchadh of Maigh Seóla (fl. early 10th century) and Gormflaith ingen Murchada. Other ancestors may have included Sigtrygg Silkbeard, Ingjald Helgasson and Ragnar Lodbrok.