Monothelitism or monotheletism (from Greek μονοθελητισμός "doctrine of one will") is a particular teaching about how the divine and human relate in the person of Jesus, known as a Christological doctrine, that formally emerged in Armenia and Syria in 629. Specifically, monothelitism is the view that Jesus Christ has two natures but only one will. This is contrary to the Christology that Jesus Christ has two wills (human and divine) corresponding to his two natures (dyothelitism). Monothelitism is a development of the Neo-chalcedonian position in the Christological debates. Formulated in 638, it enjoyed considerable popularity, even garnering patriarchal support, before being rejected and denounced as heretical in 681 at the Third Council of Constantinople.
During the 5th century, some regions of the Christian Church were thrown into confusion because of the debates that erupted over the nature of Jesus Christ. Although the Church had already determined that Christ is the son of God, just what his exact nature is remained open to debate. The Church had declared heretical the notion that Jesus is not fully divine in the 4th century (see First Council of Nicaea), during the debates over Arianism and had declared that he is God the Son become human. However, in arguing that he is both God and man, there now emerged a dispute over exactly how the human and divine natures of Christ actually exist within the person of Christ.
The Christological definition of Chalcedon, as accepted by the Eastern Orthodox, Catholic, Anglican, Lutheran, and Reformed churches, is that Christ remains in two distinct natures, yet these two natures come together within his one hypostasis. This position was opposed by the Monophysites who held that Christ possesses one nature only. The term Monophysitism of which Eutychianism is one type, held that the human and divine natures of Christ were fused into one new single (mono) nature. As described by Eutyches, his human nature was "dissolved like a drop of honey in the sea", and therefore his nature is really divine. This is distinct from Miaphysitism, which holds that, after the union, Christ is in one theanthropic (human-divine) nature and is generated from the union of two natures. The two are thus united without separation, without confusion, and without alteration, and with each having a particularity. Miaphysitism is the christological doctrine of the Oriental Orthodox churches.