Monongahela virus

Monongahela virus
Transmission electron micrograph of the Sin Nombre Hantavirus
Virus classification
Group:	Group V ((−)ssRNA)
Order:	Unassigned
Family:	Bunyaviridae
Genus:	Hantavirus
Type species
Hantaan virus
Species
Monongahela virus

Monongahela virus

Monongahela virus (MGLV) is a single-stranded, negative-sense RNA Hantavirus species of zoonotic origin that causes Hantavirus pulmonary syndrome. The virus was first isolated from a White-footed mouse (Peromyscus leucopus), indigenous to Pennsylvania after two residents died from rapid onset of respiratory failure.

Monongahela virus was first detected in P. maniculatus nubiterrae (Cloudland deer mice) captured in the Monongahela National Forest in West Virginia in 1985.

This species of Hantavirus has not been shown to transfer from person to person. Transmission by aerosolized rodent excreta still remains the only known way the virus is transmitted to humans. In general, droplet and/or fomite transfer has not been shown in the hantaviruses in either the hemorrhagic or pulmonary forms.

In both cases in Pennsylvania, the patients were living in rural areas and had recent exposure to rodent excreta prior to the onset of symptoms. Both patients developed rapid onset of respiratory distress and pulmonary edema, believed to be the result of cytokine storm, and both expired within 5 days of onset of symptoms.

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