Mitchell Henry (1826 – 22 November 1910) was an English financier, politician and Member of Parliament (MP) in the House of Commons of the United Kingdom of Great Britain and Ireland. He was MP for Galway County from 1871 to 1885, and for Glasgow Blackfriars and Hutchesontown from 1885 to 1886.
Mitchell Henry was the second son of Alexander Henry (1784–1862) of Woodlands, near Manchester, England, a very affluent cotton merchant, founder of A & S Henry & Co Ltd and Member of Parliament for South Lancashire from 1847 to 1852, who was married to Elizabeth, daughter of George Brush of Willowbrook, Killinchy, County Down, and a supporter of the Anti-Corn Law League. He was educated in London and at University College London where he read for a degree in medicine, eventually becoming a Fellow of the Royal College of Surgeons. He became a senior consultant at the Middlesex Hospital in London by the time he was 30.
After the death of his father in 1862 Mitchell Henry abandoned his career in medicine and returned to his native Manchester to run the family business. He soon became involved in politics and contested Woodstock for the Liberals in 1865, and stood in the 1867 Manchester by-election, and the 1868 general election, as a moderate Liberal, but was well-beaten in both contests. As part of his candidature in 1868 Henry started up the Manchester Evening News, though it passed out of his hands at the end of the election. He was particularly interested in the cause for a better health provision for the poor.