The Missouri Rhineland is a geographical area of Missouri that extends from west of St. Louis to slightly east of Jefferson City, located mostly in the Missouri River Valley on both sides of the river. It is named for its similarities to the Rhineland region in central Europe, a wine growing area around the Rhine river and the German-Americans who determined that this part of Missouri would be good for grape growing. The soils of the Missouri River Valley and surrounding areas are mainly rocky residual soils, which are excellent for viticulture (growing of grapes/vineyards) though poor for most agricultural purposes. These soils were left after the carbonate (mainly limestone) bedrock weathered away to impurities of clayey soil and chert fragments. Farther to the north, glacial deposits and wind-deposited loess, a silty soil also associated with the glaciers, are intermingled with the residual soils.
While the soil could support other crops, the steep slopes of these areas were better used by vineyards. Settlements date to 1801. Dutzow, the first permanent German settlement in Missouri, was founded in 1832 by Baron von Bock. German settlers established the first wineries in the mid-19th century, and later Italian immigrants also entered the industry, especially near Rolla in Phelps County.
Vineyards succeeded so well that before Prohibition, Missouri was the second-largest wine-producing state in the nation. Prohibition ruined the industry and not until the 1960s did local winemakers start to rebuild it, part of a movement in states across the country.