Minami-Matsuura (南松浦郡 Minami-Matsuura-gun?) is a district located in Nagasaki Prefecture, Japan.
As of January 1, 2009 the district has an estimated population of 22,893 and a density of 107 persons per km². The total area is 213.97 km². It forms part of the Gotō Islands.
Coordinates: 32°57′53″N 129°4′45″E / 32.96472°N 129.07917°E