Mihajlo D. Mesarovic (Serbian Latin: Mihajlo D. Mesarović, Serbian Cyrillic: Михајло Д. Месаровић; born July 2, 1928) is a Serbian scientist, who is a professor of Systems Engineering and Mathematics at Case Western Reserve University. Mesarovic has been a pioneer in the field of systems theory, he was UNESCO Scientific Advisor on Global change and also a member of the Club of Rome.
Mihajlo D. Mesarović was born on July 2, 1928 in Zrenjanin, Yugoslavia. He was awarded the B.S. from the University of Belgrade Faculty of Electrical Engineering in 1951. In 1955 he received a Ph.D. in Technical sciences from the Serbian Academy of Sciences and Arts.
From 1951 to 1955, Mesarović was a research assistant at the Nikola Tesla Institute in Belgrade. From 1955 to 1958 he was head of the inspection department of the Institute. At the same time, Mesarović held academic positions at University of Belgrade, Yugoslavia from 1954 to 1958. In 1958 he became professor at the Massachusetts Institute of Technology / USA (MIT), where he served until 1959. He was associate Professor at Case Western Reserve University from 1959 to 1964 and professor from 1964 to 1978. In that time he was head of the Systems Engineering Group 1965-68, head of the Systems Engineering Department 1968-72 and director of the Systems Research Center 1968-78. Starting 1978, Prof. Mesarović has been the Cady Staley Professor of Systems Engineering and Mathematics. One of his students was Roger W. Brockett.