Microsomal triglyceride transfer protein

MTTP
Identifiers
Aliases	MTTP, ABL, MTP, Microsomal triglyceride transfer protein
External IDs	MGI: 106926 HomoloGene: 212 GeneCards: MTTP
Gene ontology Molecular function • protein heterodimerization activity • protein binding • phospholipid transporter activity • lipid binding • lipid transporter activity Cellular component • receptor complex • endoplasmic reticulum lumen • endoplasmic reticulum Biological process • transport • phospholipid transport • lipid transport • plasma lipoprotein particle assembly • lipid metabolic process • protein secretion • triglyceride transport • chylomicron assembly • very-low-density lipoprotein particle assembly Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4547	17777
Ensembl	ENSG00000138823	ENSMUSG00000028158
UniProt	P55157	O08601
RefSeq (mRNA)	NM_001300785 NM_000253	NM_001163457 NM_008642
RefSeq (protein)	NP_000244 NP_001287714	NP_001156929.1 NP_032668.2 NP_001156929 NP_032668
Location (UCSC)	Chr 4: 99.56 – 99.62 Mb	Chr 3: 138.09 – 138.14 Mb
PubMed search

4547

17777

ENSG00000138823

ENSMUSG00000028158

P55157

O08601

NM_001300785
NM_000253

NM_001163457
NM_008642

NP_000244
NP_001287714

NP_001156929.1
NP_032668.2
NP_001156929
NP_032668

Microsomal triglyceride transfer protein large subunit is a protein that in humans is encoded by the MTTP gene.

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triaglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

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Wikipedia