Michael Palaiologos Tarchaneiotes (Greek: Μιχαήλ Παλαιολόγος Ταρχανειώτης) was a Byzantine aristocrat and general, active against the Turks in Asia Minor and against the Angevins in the Balkans from 1278 until his death from disease in 1284.
Michael Tarchaneiotes was the son of Nikephoros Tarchaneiotes, megas domestikos to John III Vatatzes (r. 1221–1254), and Maria-Martha Palaiologina, the eldest sister of Michael VIII Palaiologos (r. 1259–1261). His family supported the rise of Palaiologos to the throne in 1259, and the new emperor rewarded Michael and his brothers: they came to live in the imperial palace, while eventually Michael and his younger brother Andronikos received the high offices of protovestiarios and megas konostaulos respectively, and the third brother, John, became a general.
He first appears in the sources taking part in the 1262 campaign against the Despotate of Epirus under his uncle, John Palaiologos. In 1278, having risen to the post of megas domestikos, Tarchaneiotes accompanied his cousin, the young co-emperor Andronikos II Palaiologos (r. 1282–1328) to an expedition against the Turks in Asia Minor. The campaign was successful in driving the Turks out of the valley of the Maeander River. Tarchaneiotes, on Andronikos's orders, rebuilt, fortified, and repopulated the city of Tralles, which the young ruler intended to rename as Andronikopolis or Palaiologopolis. A few years later, however, the city, poorly supplied with water and provisions, was besieged and taken by the emir of Menteshe.