Michael Stratton
| Michael Stratton | |
|---|---|
| Born | Michael Rudolf Stratton 22 June 1957 |
| Institutions |
Wellcome Trust Sanger Institute Institute of Cancer Research Guy's Hospital University of Oxford |
| Alma mater | University of Oxford |
| Thesis | Role of genetic alterations in the genesis of human soft tissue tumours and medulloblastoma (1990) |
| Doctoral students | Nazneen Rahman |
| Known for | Cancer Genome Project |
| Notable awards |
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| Spouse | Judith Breuer (m. 1981) |
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Website www |
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Sir Michael Rudolf Stratton, FRS, FMedSci, FRCPath (born 22 June 1957) is a British clinical scientist and the third director of the Wellcome Trust Sanger Institute. He currently heads the Cancer Genome Project and is a leader of the International Cancer Genome Consortium.
Stratton was educated at the independent Haberdashers' Aske's Boys' School and obtained a medical degree from Brasenose College, the University of Oxford, and Guy's Hospital before training as a histopathologist at the Hammersmith and Maudsley Hospitals in London. He obtained a PhD while working on Medulloblastomas in the molecular biology of cancer at the Institute of Cancer Research.
Stratton has held clinical posts at Guy’s Hospital, Westminster Hospital, Hammersmith Hospital and the Royal Marsden Hospital. He took up a Faculty appointment and now holds a Professorship at the Institute of Cancer Research. He joined the Sanger Institute in 2000 and was promoted to deputy director in 2007. In May 2010, he was appointed director, succeeding Allan Bradley.
Michael Stratton's research interests are in the area of genetics of cancer. In 1994 he assembled a research group that localized BRCA2, a major breast cancer susceptibility gene that repairs chromosomal damage, to chromosome 13. The following year his team identified the gene and, in doing so generated a megabase segment of high-quality human genome sequence. His subsequent work has involved the identification of more moderate cancer susceptibility genes such as CHEK2,ATM and PALB2 each of which play a role in some breast cancers. He has additionally identified genes implicated in the development of skin, testis, colorectal and thyroid cancers, Wilms tumour and Peutz–Jeghers syndrome.
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