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Methanocaldococcus jannaschii

Methanocaldococcus jannaschii
Scientific classification
Domain: Archaea
Kingdom: Euryarchaeota
Phylum: Euryarchaeota
Class: Methanococci
Order: Methanococcales
Family: Methanocaldococcaceae
Genus: Methanocaldococcus
Species: M. jannaschii
Binomial name
Methanocaldococcus jannaschii
Synonyms
  • Methanococcus jannaschii (Jones 1983)

Methanocaldococcus jannaschii (formerly Methanococcus jannaschii) is a thermophilic methanogenic archaean in the class Methanococci. It was the first archaeon to have its complete genome sequenced. The sequencing identified many genes unique to the archaea. Many of the synthesis pathways for methanogenic cofactors were worked out biochemically in this organism, as were several other archaeal-specific metabolic pathways.

Methanocaldococcus jannaschii was isolated from a submarine hydrothermal vent at Woods Hole Oceanographic Institution.

Methanocaldococcus jannaschii was sequenced by a group at TIGR led by Craig Venter using whole-genome shotgun sequencing. Methanocaldococcus jannaschii represented the first member of the Archaea to have its genome sequenced. According to Venter, the unique features of the genome provided strong evidence that there are three domains of life.

Methanocaldoccus jannaschii is a member of the genus Methanocaldococcus (previously a part of Methanococcus) and is therefore sometimes referred to as a "class I" methanogen (e.g. [1]).

Methanocaldococcus jannaschii is a thermophilic methanogen, meaning it grows by making methane as a metabolic byproduct. It is only capable of growth on carbon dioxide and hydrogen as primary energy sources, unlike many other methanococci (such as Methanococcus maripalidus) which can also use formate as a primary energy source. The genome includes many hydrogenases, such as a 5,10-methenyltetrahydromethanopterin hydrogenase, a ferredoxin hydrogenase (eha), and a coenzyme F420 hydrogenase.


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