Metabotropic glutamate receptor 2

GRM2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4XAQ, 4XAS, 5CNI, 5CNJ
Identifiers
Aliases	GRM2, GPRC1B, MGLUR2, mGlu2, glutamate metabotropic receptor 2, mGluR2, GLUR2
External IDs	MGI: 1351339 HomoloGene: 20229 GeneCards: GRM2
Gene location (Human) Chr. Chromosome 3 (human) Band 3p21.2 Start 51,707,070 bp End 51,718,613 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 F1 Start 106,643,095 bp End 106,656,082 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • glutamate receptor activity • G-protein coupled receptor activity • group II metabotropic glutamate receptor activity • calcium channel regulator activity • signal transducer activity • protein binding Cellular component • integral component of membrane • cell projection • membrane • plasma membrane • synapse • integral component of plasma membrane • intracellular • axon • cell junction • dendrite • neuron projection • presynaptic membrane Biological process • G-protein coupled receptor signaling pathway • negative regulation of adenylate cyclase activity • glutamate secretion • signal transduction • chemical synaptic transmission • regulation of synaptic transmission, glutamatergic • adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway • G-protein coupled glutamate receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	2912	108068
Ensembl	ENSG00000164082	ENSMUSG00000023192
UniProt	Q14416	Q14BI2
RefSeq (mRNA)	NM_000839 NM_001130063 NM_001349116 NM_001349117	NM_001160353
RefSeq (protein)	NP_000830 NP_001123535 NP_001336045 NP_001336046	NP_001153825
Location (UCSC)	Chr 3: 51.71 – 51.72 Mb	Chr 3: 106.64 – 106.66 Mb
PubMed search

4XAQ, 4XAS, 5CNI, 5CNJ

2912

108068

ENSG00000164082

ENSMUSG00000023192

Q14416

Q14BI2

NM_000839
NM_001130063
NM_001349116
NM_001349117

NM_001160353

NP_000830
NP_001123535
NP_001336045
NP_001336046

NP_001153825

Metabotropic glutamate receptor 2 is a protein that in humans is encoded by the GRM2 gene.

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