Mario Ramberg Capecchi | |
---|---|
Born |
Verona, Italy |
October 6, 1937
Nationality | Italian, American |
Fields | Genetics |
Institutions |
Harvard School of Medicine University of Utah |
Alma mater |
George School Antioch College, Ohio Harvard University |
Thesis | On the Mechanism of Suppression and Polypeptide Chain Initiation (1967) |
Doctoral advisor | James D. Watson |
Known for | Knockout mouse Hox genes |
Notable awards | Kyoto Prize (1996) Franklin Medal (1997) Albert Lasker Award for Basic Medical Research (2001) Massry Prize (2002) Wolf Prize in Medicine (2002) Nobel Prize in Physiology or Medicine (2007) |
Website capecchi |
Mario Ramberg Capecchi (Verona, Italy, 6 October 1937) is an Italian-born American molecular geneticist and a co-winner of the 2007 Nobel Prize in Physiology or Medicine for discovering a method to create mice in which a specific gene is turned off, known as knockout mice. He shared the prize with Martin Evans and Oliver Smithies. He is currently Distinguished Professor of Human Genetics and Biology at the University of Utah School of Medicine.
Mario Capecchi was born in Verona, Italy, as the only child of Luciano Capecchi, an Italian airman who would be later reported as missing in action while manning an anti-aircraft gun in the Western Desert Campaign, and Lucy Ramberg, an American-born daughter of Impressionist painter Lucy Dodd Ramberg and German archaeologist Walter Ramberg. During World War II, his mother was sent to the Dachau concentration camp as punishment for pamphleteering and belonging to an anti-Fascist group. Prior to her arrest she had made contingency plans by selling her belongings and giving the proceeds to a peasant family near Bolzano to provide housing for her only child. However, after one year, the money was exhausted and the family was unable to care for him. At four-and-a-half years old he was left to fend for himself, living as a street child on the streets of northern Italy for the next four years, living in various orphanages and roving through towns with groups of other homeless children.