Mandrake

A mandrake is the root of a plant, historically derived either from plants of the genus Mandragora found in the Mediterranean region, or from other species, such as Bryonia alba, the English mandrake, which have similar properties. The plants from which the root is obtained are also called "mandrakes". Mediterranean mandrakes are perennial herbaceous plants with ovate leaves arranged in a rosette, a thick upright root, often branched, and bell-shaped flowers followed by yellow or orange berries. They have been placed in different species by different authors. They are very variable perennial herbaceous plants with long thick roots (often branched) and almost no stem. The leaves are borne in a basal rosette, and are very variable in size and shape, with a maximum length of 45 cm (18 in). They are usually either elliptical in shape or wider towards the end (obovate), with varying degrees of hairiness.

Because mandrakes contain deliriant hallucinogenic tropane alkaloids and the shape of their roots often resembles human figures, they have been associated with a variety of superstitious practices throughout history. They have long been used in magic rituals, today also in contemporary pagan traditions such as Wicca and Odinism.

All species of Mandragora contain highly biologically active alkaloids, tropane alkaloids in particular. The alkaloids make the plant, in particular the root and leaves, poisonous, via anticholinergic, hallucinogenic, and hypnotic effects. Anticholinergic properties can lead to asphyxiation. Accidental poisoning is not uncommon. Ingesting mandrake root is likely to have other adverse effects such as vomiting and diarrhea. The alkaloid concentration varies between plant samples. Clinical reports of the effects of consumption of Mediterranean mandrake include severe symptoms similar to those of atropine poisoning, including blurred vision, dilation of the pupils (mydriasis), dryness of the mouth, difficulty in urinating, dizziness, headache, vomiting, blushing and a rapid heart rate (tachycardia). Hyperactivity and hallucinations also occurred in the majority of patients.

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