Major basic protein

PRG2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1H8U, 2BRS, 4QXX
Identifiers
Aliases	PRG2, BMPG, MBP, MBP1, proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein), proMBP, proteoglycan 2, pro eosinophil major basic protein
External IDs	OMIM: 605601 MGI: 103294 HomoloGene: 2044 GeneCards: PRG2
Gene location (Human) Chr. Chromosome 11 (human) Band 11q12.1 Start 57,386,794 bp End 57,390,657 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2 D|2 49.45 cM Start 84,980,461 bp End 84,983,632 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • heparin binding • carbohydrate binding Cellular component • extracellular region • transport vesicle • cytoplasmic vesicle • extracellular exosome • ficolin-1-rich granule lumen Biological process • defense response to bacterium • immune system process • regulation of cytokine biosynthetic process • defense response to nematode • negative regulation of interleukin-10 production • positive regulation of interleukin-4 production • immune response • neutrophil degranulation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	5553	19074
Ensembl	ENSG00000186652	ENSMUSG00000027073
UniProt	P13727	Q61878
RefSeq (mRNA)	NM_002728 NM_001243245 NM_001302926 NM_001302927	NM_008920
RefSeq (protein)	NP_001230174 NP_001289855 NP_001289856 NP_002719	NP_032946
Location (UCSC)	Chr 11: 57.39 – 57.39 Mb	Chr 11: 84.98 – 84.98 Mb
PubMed search

1H8U, 2BRS, 4QXX

5553

19074

ENSG00000186652

ENSMUSG00000027073

P13727

Q61878

NM_002728
NM_001243245
NM_001302926
NM_001302927

NM_008920

NP_001230174
NP_001289855
NP_001289856
NP_002719

NP_032946

Proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein), also known as PRG2, is a protein which in humans is encoded by the PRG2 gene.

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Wikipedia