MYO6

MYO6
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2N11, 2N13, 2N0Z, 2N10, 2N12
Identifiers
Aliases	MYO6, DFNA22, DFNB37, myosin VI
External IDs	MGI: 104785 HomoloGene: 56417 GeneCards: MYO6
Gene ontology Molecular function • motor activity • actin filament binding • ATP binding • calmodulin binding • protein binding • minus-end directed microfilament motor activity • ADP binding • actin binding • nucleotide binding • cadherin binding Cellular component • myosin complex • nucleus • intracellular membrane-bounded organelle • cell projection • ruffle membrane • DNA-directed RNA polymerase II, holoenzyme • nucleoplasm • lysosomal membrane • perinuclear region of cytoplasm • clathrin-coated endocytic vesicle • protein complex • apical part of cell • clathrin-coated vesicle membrane • ruffle • cytosol • extracellular exosome • membrane • clathrin-coated pit • filamentous actin • plasma membrane • nuclear membrane • cytoplasm • cell cortex • microvillus • Golgi apparatus • unconventional myosin complex • endocytic vesicle • cytoplasmic vesicle Biological process • intracellular protein transport • actin filament-based movement • regulation of secretion • sensory perception of sound • positive regulation of transcription from RNA polymerase II promoter • protein transport • transport • endocytosis • DNA damage response, signal transduction by p53 class mediator • response to drug Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4646	17920
Ensembl	ENSG00000196586	ENSMUSG00000033577
UniProt	Q9UM54	Q64331
RefSeq (mRNA)	NM_001300899 NM_004999	NM_001039546 NM_008662
RefSeq (protein)	NP_001287828 NP_004990	n/a
Location (UCSC)	Chr 6: 75.75 – 75.92 Mb	Chr 9: 80.17 – 80.31 Mb
PubMed search

2N11, 2N13, 2N0Z, 2N10, 2N12

4646

17920

ENSG00000196586

ENSMUSG00000033577

Q9UM54

Q64331

NM_001300899
NM_004999

NM_001039546
NM_008662

NP_001287828
NP_004990

n/a

Myosin VI, also known as MYO6, is a protein. It has been found in humans, mice, fruit flies (Drosophila melanogaster), and nematodes (Caenorhabditis elegans).

Myosin VI is a molecular motor involved in intracellular vesicle and organelle transport. It is one of the so-called unconventional myosins.[supplied by OMIM]

...
Wikipedia