MYO15A

MYO15A
Identifiers
Aliases	MYO15A, DFNB3, MYO15, myosin XVA
External IDs	MGI: 1261811 HomoloGene: 56504 GeneCards: MYO15A
Gene ontology Molecular function • nucleotide binding • actin binding • motor activity • ATP binding • calmodulin binding Cellular component • cytoplasm • stereocilium bundle • cell projection • extracellular exosome • cytoskeleton • myosin complex • stereocilium Biological process • sensory perception of sound • inner ear morphogenesis • locomotory behavior Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51168	17910
Ensembl	ENSG00000091536	ENSMUSG00000042678
UniProt	Q9UKN7	Q9QZZ4
RefSeq (mRNA)	NM_016239	NM_001103171 NM_010862 NM_182698
RefSeq (protein)	NP_057323	NP_001096641 NP_034992 NP_874357
Location (UCSC)	Chr 17: 18.11 – 18.18 Mb	Chr 11: 60.47 – 60.53 Mb
PubMed search

51168

17910

ENSG00000091536

ENSMUSG00000042678

Q9UKN7

Q9QZZ4

NM_016239

NM_001103171
NM_010862
NM_182698

NP_057323

NP_001096641
NP_034992
NP_874357

Myosin-XV is a protein that in humans is encoded by the MYO15A gene.

Read-through transcript containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined.

This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea.

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Wikipedia