MYH14

MYH14
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5JLH
Identifiers
Aliases	MYH14, DFNA4, DFNA4A, MHC16, MYH17, NMHC II-C, NMHC-II-C, PNMHH, myosin, FP17425, myosin, heavy chain 14, non-muscle
External IDs	MGI: 1919210 HomoloGene: 23480 GeneCards: MYH14
Gene ontology Molecular function • nucleotide binding • actin-dependent ATPase activity • calmodulin binding • actin filament binding • microfilament motor activity • actin binding • motor activity • ATP binding • ATPase activity Cellular component • cytoplasm • cytosol • myosin II filament • membrane • growth cone • myelin sheath • stress fiber • axon • brush border • myosin II complex • actomyosin • extracellular exosome • myosin complex Biological process • skeletal muscle contraction • actomyosin structure organization • sensory perception of sound • actin filament-based movement • vocalization behavior • regulation of cell shape • mitochondrion morphogenesis • skeletal muscle tissue development • neuronal action potential Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	79784	71960
Ensembl	ENSG00000105357	ENSMUSG00000030739
UniProt	Q7Z406	Q6URW6
RefSeq (mRNA)	NM_001077186 NM_001145809 NM_024729	NM_001271538 NM_001271540 NM_028021
RefSeq (protein)	NP_001070654 NP_001139281 NP_079005	NP_001258467.1 NP_001258469.1 NP_082297.1 NP_001258467 NP_001258469 NP_082297
Location (UCSC)	Chr 19: 50.19 – 50.31 Mb	Chr 7: 44.61 – 44.67 Mb
PubMed search

5JLH

79784

71960

ENSG00000105357

ENSMUSG00000030739

Q7Z406

Q6URW6

NM_001077186
NM_001145809
NM_024729

NM_001271538
NM_001271540
NM_028021

NP_001070654
NP_001139281
NP_079005

NP_082297

Myosin-14 is a protein that in humans is encoded by the MYH14 gene.

This gene encodes a member of the myosin superfamily. Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene.

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