MTMR12

MTMR12
Identifiers
Aliases	MTMR12, 3-PAP, PIP3AP, myotubularin related protein 12
External IDs	MGI: 2443034 HomoloGene: 10403 GeneCards: MTMR12
Gene location (Human) Chr. Chromosome 5 (human) Band 5p13.3 Start 32,226,994 bp End 32,313,009 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15|15 A1 Start 12,205,028 bp End 12,272,240 bp
Gene ontology Molecular function • protein binding • phosphatase regulator activity Cellular component • cytoplasm • cytosol Biological process • toxin transport • regulation of catalytic activity • phosphatidylinositol biosynthetic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54545	268783
Ensembl	ENSG00000150712	ENSMUSG00000039458
UniProt	Q9C0I1	Q80TA6
RefSeq (mRNA)	NM_001040446 NM_001294343 NM_001294344 NM_019061	NM_172958
RefSeq (protein)	NP_001035536 NP_001281272 NP_001281273	NP_766546
Location (UCSC)	Chr 5: 32.23 – 32.31 Mb	Chr 5: 12.21 – 12.27 Mb
PubMed search

54545

268783

ENSG00000150712

ENSMUSG00000039458

Q9C0I1

Q80TA6

NM_001040446
NM_001294343
NM_001294344
NM_019061

NM_172958

NP_001035536
NP_001281272
NP_001281273

NP_766546

Myotubularin related protein 12 is a protein that in humans is encoded by the MTMR12 gene.

Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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