MST1R

MST1R
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3PLS, 4FWW, 4QT8
Identifiers
Aliases	MST1R, CD136, CDw136, PTK8, RON, macrophage stimulating 1 receptor, NPCA3
External IDs	MGI: 99614 HomoloGene: 1835 GeneCards: MST1R
Gene ontology Molecular function • transferase activity • nucleotide binding • protein kinase activity • macrophage colony-stimulating factor receptor activity • kinase activity • protein binding • enzyme binding • transmembrane receptor protein tyrosine kinase activity • protein tyrosine kinase activity • ATP binding Cellular component • integral component of membrane • membrane • integral component of plasma membrane • stress fiber • cell surface • vacuole • plasma membrane Biological process • defense response • movement of cell or subcellular component • positive regulation of protein kinase B signaling • positive regulation of MAP kinase activity • phosphorylation • transmembrane receptor protein tyrosine kinase signaling pathway • immune system process • response to virus • single fertilization • protein phosphorylation • positive regulation of cell proliferation • peptidyl-tyrosine phosphorylation • innate immune response • signal transduction • macrophage colony-stimulating factor signaling pathway • hepatocyte growth factor receptor signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4486	19882
Ensembl	ENSG00000164078	ENSMUSG00000032584
UniProt	Q04912	Q62190
RefSeq (mRNA)	NM_001244937 NM_002447 NM_001318913	NM_001287261 NM_009074
RefSeq (protein)	NP_001231866 NP_001305842 NP_002438	NP_001274190 NP_033100
Location (UCSC)	Chr 3: 49.89 – 49.9 Mb	Chr 9: 107.91 – 107.92 Mb
PubMed search

3PLS, 4FWW, 4QT8

4486

19882

ENSG00000164078

ENSMUSG00000032584

Q04912

Q62190

NM_001244937
NM_002447
NM_001318913

NM_001287261
NM_009074

NP_001231866
NP_001305842
NP_002438

NP_001274190
NP_033100

Macrophage-stimulating protein receptor is a protein that in humans is encoded by the MST1R gene. MST1R is also known as RON (Recepteur d'Origine Nantais) kinase, named after the French city in which it was discovered. It is related to the c-MET receptor tyrosine kinase.

...
Wikipedia