MRNA (guanine-N7-)-methyltransferase

mRNA (guanine-N7-)-methyltransferase
Identifiers
EC number	2.1.1.56
CAS number	56941-25-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
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PMC	articles
PubMed	articles
NCBI	proteins

RNMT
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3BGV, 3EPP, 5E9J, 5E9W, 5E8J
Identifiers
Aliases	RNMT, MET, RG7MT1, hCMT1c, CMT1, CMT1c, cm1p, hCMT1, hMet, MRNA-methyltransferase, RNA guanine-7 methyltransferase
External IDs	MGI: 1915147 HomoloGene: 2816 GeneCards: RNMT
Gene location (Human) Chr. Chromosome 18 (human) Band 18p11.21 Start 13,726,660 bp End 13,764,558 bp
Gene location (Mouse) Chr. Chromosome 18 (mouse) Band 18|18 E2 Start 68,300,355 bp End 68,324,852 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • methyltransferase activity • transferase activity • mRNA (guanine-N7-)-methyltransferase activity • protein binding • RNA binding Cellular component • mRNA cap binding complex • receptor complex • nucleus • nucleoplasm • fibrillar center • mRNA cap methyltransferase complex Biological process • mRNA processing • methylation • transcription from RNA polymerase II promoter • RNA 5'-cap (guanine-N7)-methylation • cellular response to leukemia inhibitory factor • 7-methylguanosine mRNA capping Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8731	67897
Ensembl	ENSG00000101654	ENSMUSG00000009535
UniProt	O43148	Q9D0L8
RefSeq (mRNA)	NM_001308263 NM_003799	NM_001170953 NM_026440
RefSeq (protein)	NP_001295192 NP_003790	NP_001164424 NP_080716
Location (UCSC)	Chr 18: 13.73 – 13.76 Mb	Chr 18: 68.3 – 68.32 Mb
PubMed search

3BGV, 3EPP, 5E9J, 5E9W, 5E8J

8731

67897

ENSG00000101654

ENSMUSG00000009535

O43148

Q9D0L8

NM_001308263
NM_003799

NM_001170953
NM_026440

NP_001295192
NP_003790

NP_001164424
NP_080716

In enzymology, a mRNA (guanine-N7-)-methyltransferase also known as mRNA cap guanine-N7 methyltransferase is an enzyme that catalyzes the chemical reaction

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Wikipedia