MICAL1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1WYL, 2CO8

Identifiers

MICAL1, MICAL, MICAL-1, NICAL, microtubule associated monooxygenase, calponin and LIM domain containing 1

External IDs

Gene ontology
Molecular function	• SH3 domain binding • oxidoreductase activity • actin binding • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen • FAD binding • Rab GTPase binding • protein binding • metal ion binding • protein kinase binding • monooxygenase activity
Cellular component	• cytoplasm • cytoskeleton • intermediate filament • hippocampal mossy fiber expansion • cytosol
Biological process	• negative regulation of protein phosphorylation • actin filament depolymerization • sulfur oxidation • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • negative regulation of apoptotic process • oxidation-reduction process • cytoskeleton organization • signal transduction • regulation of regulated secretory pathway • blood coagulation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


64780


171580


ENSG00000135596


ENSMUSG00000019823


Q8TDZ2


Q8VDP3

RefSeq (mRNA)


NM_022765 NM_001159291 NM_001286613


NM_001164433 NM_138315

RefSeq (protein)


NP_001152763 NP_001273542 NP_073602


NP_001157905 NP_612188

Location (UCSC)

PubMed search

NEDD9-interacting protein with calponin homology and LIM domains is a protein that in humans is encoded by the MICAL1 gene.

MICAL1 has been shown to interact with NEDD9 and RAB1A.