Loul Sessène (or Loul Séssène) is a village in Senegal located in the Sine-Saloum area, in the West of the country.
It is the chef-lieu of the rural community of Loul Sessène, located in the Fimela Arrondissement, of the Fatick Department and the Region of Fatick.
Loul Sessène is located in the territory of the former Kingdom of Sine. In pre-colonial times, the Loul - a Serer title of nobility - resided in Loul Sessène, founded by the Sène family.
In 2003, the population was 3,601 with 407 houses.
Coordinates: 14°18′N 16°36′W / 14.300°N 16.600°W