"Lost Without U" is a song by American recording artist Robin Thicke. It was released in January 2007 as the second single from his second album, The Evolution of Robin Thicke (2006). People magazine voted the ballad as 2007 sexiest song of the year. It was also named the 10th best song of 2007 by Vibe magazine.

"Lost Without U" was written after the release of Robin Thicke's first album and while he was on tour. It was at a time he was feeling insecure and wasn't having much commercial success with his music. Thicke said the following to MTV News about the inspiration for the song: "I was going through an insecure period and wanted my lady to tell me how fabulous and how sexy and how wonderful I am."

Thicke appears in the music video of the song alongside his now ex-wife, actress Paula Patton. Fearful that the video for this single would be the last one he would ever make, Thicke chose to cast his wife as the leading lady in the music video as a way to tell the truth and represent how the last few years of his life have been. However, with the success of "Lost Without U" Thicke went on to film a new video for the follow-up single, "Can U Believe".

Throughout the video, scenes are intercut of Thicke sitting on a chair playing his acoustic guitar and on a wall with a light flashing on him. The video begins with Thicke entering his apartment; he seems to be angry as he throws his keys to the floor. However, he is then seen on a bed, caressing his wife and kissing her shoulder. After, he is in a bathroom, where he imagines his wife taking off his clothes, though he is taking them off himself. After, his wife is shown in the shower, and he is shown singing. He is then shown sitting on a couch, and his wife walks up to him and sits on the couch suggestively, but then gets up and leaves. They are then shown in a bedroom, with Thicke's wife dancing and Thicke watching while holding a pair of socks (presumably hers). They are then shown on top of a building, enjoying each other's presence. Thicke is shown back in his apartment angry, when all of a sudden his wife walks in, and she lets her jacket fall off her, exposing a revealing outfit. They begin kissing passionately, and Thicke lifts her up, but is then shown alone, confused (he had dreamed the kissing session).

"Lost Without U" has been known as Thicke's breakthrough single on the Billboard Hot 100, peaking at number 14 on the chart and became his biggest hit until 2013's "Blurred Lines". The song is his first single to chart on the Hot 100 from the album The Evolution of Robin Thicke.

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