Liver sinusoid

Liver sinusoid
Sinusoid of a rat liver with fenestrated endothelial cells. Fenestrae are approx 100 nm diameter, and the sinusoidal width 5 µm.
Basic liver structure
Details
Identifiers
Latin	vas sinusoideum
TH	H3.04.05.0.00014
FMA	17543
Anatomical terminology []

A liver sinusoid is a type of sinusoidal blood vessel (with fenestrated, discontinuous endothelium) that serves as a location for mixing of the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein.

are separated from the sinusoids by the space of Disse. Kupffer cells are located inside the sinusoids and can take up and destroy foreign material such as bacteria.

The sinusoidal endothelial cells are cultured for a variety of research purposes. The utility of these cells are of particular interest. One problem to overcome is the reversing of cellular differentiation that has made these cells highly specialized phenotypically in vitro.

Human liver sinusoid

A single lobule of the liver of a pig. X 60.