Lipoprotein(a)

LPA
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 1I71, 1JFN, 1KIV, 2FEB, 4BV5, 4BV7, 4BVC, 4BVD, 4BVV, 4BVW, 3KIV, 4KIV
Identifiers
Aliases	LPA, AK38, APOA, LP, Lipoprotein(a)
External IDs	HomoloGene: 87856 GeneCards: LPA
Genetically Related Diseases
coronary artery disease
Gene ontology Molecular function • fibronectin binding • apolipoprotein binding • peptidase activity • endopeptidase inhibitor activity • heparin binding • serine-type endopeptidase activity • serine-type peptidase activity • protein binding • hydrolase activity Cellular component • extracellular region • plasma lipoprotein particle Biological process • lipoprotein metabolic process • lipid transport • blood circulation • proteolysis • lipid metabolic process • transport • negative regulation of endopeptidase activity Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4018	n/a
Ensembl	ENSG00000198670	n/a
UniProt	P08519	n/a
RefSeq (mRNA)	NM_005577	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	Chr 6: 160.53 – 160.66 Mb	n/a
PubMed search		n/a

1I71, 1JFN, 1KIV, 2FEB, 4BV5, 4BV7, 4BVC, 4BVD, 4BVV, 4BVW, 3KIV, 4KIV

4018

n/a

ENSG00000198670

n/a

P08519

n/a

NM_005577

n/a

n/a

n/a

Lipoprotein(a) (also called Lp(a) or LPA) is a lipoprotein subclass. Genetic studies and numerous epidemiologic studies have identified Lp(a) as a risk factor for atherosclerotic diseases such as coronary heart disease and stroke.

Lipoprotein(a) was discovered in 1963 by Kåre Berg and the human gene encoding apolipoprotein(a) was cloned in 1987.

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Wikipedia