"Like You'll Never See Me Again" is a song by American singer Alicia Keys from her third studio album As I Am (2007). Written and produced by Keys and Kerry Brothers, Jr., it was released in November 2007 as the album's second single. The song was first heard on October 25, 2007 on Atlanta's V103 WVEE radio station. An official remix of the song featuring rapper Ludacris exists.

Upon its release, the song peaked at number twelve on the Billboard Hot 100 and became Keys' second consecutive R&B chart-topper, remaining atop the Hot R&B/Hip-Hop Songs chart for seven weeks. It was ranked number forty-seven on Billboard's Top Hot 100 Hits of 2008. The song went on to replace "No One" at number one on the US R&B/Hip-Hop charts. In 2008, the song won two NAACP Image Awards for Outstanding Music Video and Outstanding Song and an ASCAP Rhythm & Soul Music Award for Top R&B/Hip-Hop Song.

In January 2008, it was used in advertisements for the ABC soap opera All My Children, hyping the return of supercouple Jesse Hubbard and Angie Baxter. The song was used once again in the February 15, 2008 episode of the series, when the couple was reunited after twenty years.

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