Leukotriene C4 synthase

LTC4S

Protein LTC4S PDB 2PNO.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4JRZ, 2PNO, 2UUH, 2UUI, 3B29, 3HKK, 3LEO, 3PCV, 4J7T, 4J7Y, 4JC7, 4JCZ, 5HV9, 4WAB

Identifiers

LTC4S, entrez:4056, Leukotriene C4 synthase

External IDs

OMIM: 246530 MGI: 107498 HomoloGene: 7406 GeneCards: LTC4S

Gene ontology
Molecular function	• glutathione transferase activity • leukotriene-C4 synthase activity • glutathione peroxidase activity • protein binding • lyase activity • enzyme activator activity • lipid binding
Cellular component	• integral component of membrane • endoplasmic reticulum membrane • membrane • nuclear envelope • endoplasmic reticulum • nuclear outer membrane • nucleus • intracellular membrane-bounded organelle
Biological process	• leukotriene metabolic process • positive regulation of catalytic activity • lipoxygenase pathway • leukotriene biosynthetic process • lipoxin metabolic process • cellular oxidant detoxification
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


4056


17001


ENSG00000213316


ENSMUSG00000020377


Q16873


Q60860

RefSeq (mRNA)


NM_145867


NM_008521 NM_001313968

RefSeq (protein)


NP_665874


NP_032547.1 NP_001300897 NP_032547

Location (UCSC)

Chr 5: 179.79 – 179.8 Mb

Chr 11: 50.24 – 50.24 Mb

PubMed search

4JRZ, 2PNO, 2UUH, 2UUI, 3B29, 3HKK, 3LEO, 3PCV, 4J7T, 4J7Y, 4JC7, 4JCZ, 5HV9, 4WAB

ENSG00000213316

ENSMUSG00000020377

NM_008521
NM_001313968

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Wikipedia

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