Lefortovo Prison
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| Location | Moscow, Russia |
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| Coordinates | 55°45′40″N 37°42′22″E / 55.7611407°N 37.7062039°E |
| Status | operational |
| Security class | detention center |
| Opened | 1881 |
| Managed by | Ministry of Justice of the RF |
Lefortovo Prison (Russian: Лефортовская тюрьма) is a prison in Moscow, Russia, which, since 2005, has been under the jurisdiction of the Ministry of Justice of the Russian Federation. It was built in 1881. It was named after the Lefortovo District of Moscow where it is located, which in turn took its name from Franz Lefort, a close associate of Tsar Peter I the Great.
During the Great Purge, Lefortovo prison was used by NKVD for interrogations with torture. Lefortovo was an infamous KGB prison and investigative isolator (Russian: СИЗО, следственный изолятор) in the Soviet Union for detainment of political prisoners. In 1994, it was transferred to the MVD; and, from 1996 to 2005, it was handed back to the FSB, a successor of the KGB.
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