Laurie Glimcher

Laurie Glimcher
Born	Laurie Glimcher 1951
Residence	United States
Education	Radcliffe College(1968-1972 B.A. 1972) Harvard Medical School (1976)
Known for	Cancer Immunotherapy (research) Immune System (research) Osteoporosis (Clinical Specialty)

Radcliffe College(1968-1972 B.A. 1972)

Laurie Hollis Glimcher is an American physician-scientist who was appointed President and CEO of Dana-Farber Cancer Institute in February 2016. Laurie Glimcher is the daughter of Melvin Glimcher, who was a pioneer in the development in of artificial limbs while the chair of the Massachusetts General Hospital Orthopedics Department. She is the wife of Gregory A. Petsko, head of biochemistry at Brandeis University. Glimcher followed in the footsteps of her father by later becoming a full professor at Harvard; the two became research partners. Laurie Glimcher has been a pioneering force in the immerging field of osteobiology and immunology. She is a member of the National Academy of Sciences. She received the L'Oréal-UNESCO Awards for Women in Science in 2014 for her work in the field of immunology and her research regarding the control of immune responses. Glimcher received her bachelor's degree at Radcliffe College in 1972 and her M.D. at Harvard Medical School in 1976.

Glimcher's research has focused on the immune system; she is known for early work with T cell differentiation, her discovery that Schnurri-3 regulates osteoblasts which led to a collaboration with Merck & Co., and her discovery of the role played by XBP-1 in lipogenesis and the unfolded protein response. Glimcher's role helped discover Schnurri-3 (Shn3 for short) is a large zinc finger protein distantly related to Drosophila. Shn is a potent and essential regulator of adult bone formation. Her research has had implications for understanding asthma, HIV, inflammatory bowel disease, and osteoporosis, and around 2016, on cancer immunotherapy.

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