Lamin B

LMNB2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LLL, 5BNW
Identifiers
Aliases	LMNB2, lamin B2, LAMB2, LMN2, EPM9
External IDs	MGI: 96796 HomoloGene: 7818 GeneCards: LMNB2
Gene ontology Molecular function • structural molecule activity Cellular component • intermediate filament • nucleus • membrane • nuclear inner membrane • lamin filament • nuclear envelope Biological process • biological process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	84823	16907
Ensembl	ENSG00000176619	ENSMUSG00000062075
UniProt	Q03252	P21619
RefSeq (mRNA)	NM_032737	NM_010722 NM_001347140
RefSeq (protein)	NP_116126	NP_001334069 NP_034852
Location (UCSC)	Chr 19: 2.43 – 2.46 Mb	Chr 10: 80.9 – 80.92 Mb
PubMed search

2LLL, 5BNW

84823

16907

ENSG00000176619

ENSMUSG00000062075

Q03252

P21619

NM_032737

NM_010722
NM_001347140

NP_116126

NP_001334069
NP_034852

Lamin B2 is a protein that in humans is encoded by the LMNB2 gene. It is the second of two type B nuclear lamins, and it is associated with laminopathies.

Model organisms have been used in the study of Lamin B2 function. A conditional knockout mouse line, called Lmnb2^{tm1a(KOMP)Wtsi} was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.

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Wikipedia