Lake Wayne formed in the Lake Erie and Lake St. Clair basins around 12,500 years before present (YBP) when Lake Arkona dropped in eleveation. About 20 feet (6.1 m) below the Lake Warren beaches it was early described as a lower Lake Warren level. Based on work in Wayne County, near the village of Wayne evidence was found that Lake Wayne succeeded Lake Whittlesey and preceded Lake Warren. From the Saginaw Basin the lake did not discharge water through Grand River but eastward along the edge of the ice sheet to Syracuse, New York, thence into the Mohawk valley. This shift in outlets warranted a separate from Lake Warren. The Wayne beach lies but a short distance inside the limits of the Warren beach. Its character is not greatly different when taken throughout its length in Michigan, Ohio, Pennsylvania and New York. At the type locality in Wayne County, Michigan, it is a sandy ridge, but farther north, and to the east through Ohio it is gravel. The results of the isostatic rebound area similar to the Lake Warren beaches.
The Wayne beach is below the level of the Lake Warren beach. It appears to be the older, for it shows evidence of submergence and modification. The Wayne beach was submerged and modified during Lake Warren. The lowest stage of Lake Wayne may have coincided with the earliest stages of Lake Algonquin
Lake Wayne was correlated with the Two Creeks Interstade and with eastward drainage into the Hudson River. Field studies in western New York are inconclusive. Based on studies of the Buffalo Moraine, the Alden Moraine, and the Niagara Falls Moraine it is believed that a local series of rapid glacial melting led to sand and gravel deposition, followed by an advance of the ice sheet. Because subdued pebble beach ridges, the Wayne Lake may have persisted until the ice margin had retreated north to near the Niagara Falls Moraine. This would raise the lake level to form the Warren III lake.