Keratin 2

KRT2
Identifiers
Aliases	KRT2, CK-2e, K2e, KRT2A, KRT2E, KRTE, keratin 2
External IDs	OMIM: 600194 HomoloGene: 30974 GeneCards: KRT2
Gene ontology Molecular function • structural constituent of cytoskeleton • protein binding • structural molecule activity • cytoskeletal protein binding Cellular component • keratin filament • extracellular exosome • membrane • nucleus • intermediate filament • extracellular space • cytosol Biological process • keratinocyte migration • keratinocyte activation • keratinocyte proliferation • intermediate filament organization • epidermis development • keratinocyte development • keratinization • cornification Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3849	n/a
Ensembl	ENSG00000172867	n/a
UniProt	P35908	n/a
RefSeq (mRNA)	NM_000423	n/a
RefSeq (protein)	NP_000414	n/a
Location (UCSC)	Chr 12: 52.64 – 52.65 Mb	n/a
PubMed search		n/a

3849

n/a

ENSG00000172867

n/a

P35908

n/a

NM_000423

n/a

NP_000414

n/a

Keratin 2A also known as keratin 2E or keratin 2 is a protein that in humans is encoded by the KRT2A gene.

Keratin 2A is a type II cytokeratin. It is found largely in the upper spinous layer of epidermal keratinocytes and mutations in the gene encoding this protein have been associated with ichthyosis bullosa of Siemens.

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Wikipedia