Keratin 17

KRT17
Identifiers
Aliases	KRT17, K17, PC, PC2, PCHC1, 39.1, CK-17, keratin 17
External IDs	OMIM: 148069 MGI: 96691 HomoloGene: 363 GeneCards: KRT17
Gene ontology Molecular function • structural constituent of cytoskeleton • MHC class II receptor activity • protein binding • structural molecule activity • MHC class II protein binding Cellular component • cytoplasm • extracellular exosome • intermediate filament • cell periphery • cytosol • intermediate filament cytoskeleton Biological process • morphogenesis of an epithelium • positive regulation of hair follicle development • hair follicle morphogenesis • intermediate filament organization • positive regulation of cell growth • positive regulation of translation • signal transduction • epidermis development • keratinization • cornification Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3872	16667
Ensembl	ENSG00000128422	ENSMUSG00000035557
UniProt	Q04695	Q9QWL7
RefSeq (mRNA)	NM_000422	NM_010663
RefSeq (protein)	NP_000413	NP_034793.1 NP_034793
Location (UCSC)	Chr 17: 41.62 – 41.62 Mb	Chr 11: 100.26 – 100.26 Mb
PubMed search

3872

16667

ENSG00000128422

ENSMUSG00000035557

Q04695

Q9QWL7

NM_000422

NM_010663

NP_000413

NP_034793.1
NP_034793

Keratin, type I cytoskeletal 17 is a protein that in humans is encoded by the KRT17 gene.

Keratin 17 is a type I cytokeratin. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in the gene encoding this protein lead to Jackson-Lawler type pachyonychia congenita and .

Keratin 17 has been shown to interact with CCDC85B.

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Wikipedia