Kayabe (茅部郡 Kayabe-gun?) is a district located in Oshima Subprefecture, Hokkaido, Japan.
As of 2004, the district has an estimated population of 24,463 and a density of 51.09 persons per km². The total area is 478.82 km².
Coordinates: 42°04′08″N 140°37′19″E / 42.069°N 140.622°E