Karasuyama Domain (烏山藩 Karasuyama-han?) was a feudal domain under the Tokugawa shogunate of Edo period Japan, located in the Nasu region of northern Shimotsuke Province (modern-day ), Japan. It was centered on Karasuyama Castle in what is now part of the city of . Karasuyama was ruled by a number of clans in its early history, but was ruled by a junior branch of the Ōkubo clan from the mid-Edo period onwards. The Karasuyama Ōkubo clan maintained a secondary jin'ya in what is now Atsugi, Kanagawa to administer its extensive holdings in Sagami Province.
The Nasu clan ruled the Nasu district of northern Shimotsuke Province from the Kamakura period. During the late Sengoku period, partly for failing to participate in the 1590 Battle of Odawara, Toyotomi Hideyoshi divided their holdings, creating Nasu Domain (20,000 koku) for the Nasu clan, and awarding their ancestral castle, Karasuyama Castle and 20,000 koku to Narita Ujinaga. The Narita were vassals of the Odawara Hōjō, who pledged allegiance to the Toyotomi after the fall of their liege. Ujinaga’s son Narita Ujitada fought on the side of Tokugawa Ieyasu against the Uesugi clan and in the Battle of Sekigahara and was awarded an increase to 37,000 koku. His son, Narita Ujimune died without heir in 1622 and the clan was reduced to hatamoto status.