Kamiiso (上磯町 Kamiiso-chō?) was a town located in Kamiiso District, Oshima Subprefecture, Hokkaido, Japan.
As of 2004, the town had an estimated population of 36,887 and a density of 140.57 persons per km². The total area was 262.41 km².
On February 1, 2006, Kamiiso was merged with the town of Ōno (from Kameda District) to form the new city of Hokuto.