Kalākua Kaheiheimālie, later known as Hoapili Wahine (c. 1778–1842) was a member of Hawaiian royalty who was one of the Queen consorts at the founding of the Kingdom of Hawaii. She was mother of another Queen consort, and grandmother of two future kings. Some sources call her Kaheiheimaile rather than Kaheiheimālie. "Mālie" means serene while the "maile" is the vine Alyxia olivaeformis. The second spelling seems to be older and more appropriate.

She was born c. 1778 into a noble (ali'i) family of Maui. Her father was Keʻeaumoku Pāpaʻiahiahi, a noble from Hawaiʻi Island. Her mother was Nāmāhānaʻi Kaleleokalani, the former consort of her half-brother the late king of Maui, Kamehameha Nui. From her mother she was a member of the royal house of Maui. Her siblings included Hawaiʻi island Governor John Adams Kuakini, Queen Kaʻahumanu, Maui Governor George Cox Kahekili Keʻeaumoku II, and Lydia Namahana Piʻia. Her father became an advisor and friend to Kamehameha I, eventually becoming royal governor of Maui. He arranged for her sister Kaʻahumanu to marry the king when she was thirteen; she would be the most powerful leader of the kingdom for several decades.

First Kaheiheimālie married Prince Kalaʻimamahu, Chief Priest of ʻIo and Kāne. He was a brother of Kamehameha I. They divorced around 1795 and she married her former brother-in-law King Kamehameha I in a ceremony known as Hoao-Wohi. She was part of the court of Kamehameha I that met George Vancouver during his expedition in 1794 and agreed to the first treaty with Great Britain.

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