KLF14

KLF14
Identifiers
Aliases	KLF14, BTEB5, Kruppel-like factor 14, Kruppel like factor 14
External IDs	MGI: 3577024 HomoloGene: 76469 GeneCards: KLF14
Gene ontology Molecular function • DNA binding • metal ion binding • nucleic acid binding Cellular component • nucleus Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	136259	619665
Ensembl	ENSG00000266265	ENSMUSG00000073209
UniProt	Q8TD94	Q19A41
RefSeq (mRNA)	NM_138693	NM_001135093
RefSeq (protein)	n/a	NP_001128565.1 NP_001128565
Location (UCSC)	Chr 7: 130.73 – 130.73 Mb	Chr 6: 30.96 – 30.96 Mb
PubMed search

136259

619665

ENSG00000266265

ENSMUSG00000073209

Q8TD94

Q19A41

NM_138693

NM_001135093

n/a

NP_001128565.1
NP_001128565

Krüppel-like factor 14, also known as basic transcription element-binding protein 5 (BTEB5) is a protein that in humans is encoded by the KLF14 gene. The corresponding Klf14 mouse gene is known as Sp6.

KLF14 is a member of the Krüppel-like factor family of transcription factors. It regulates the transcription of various genes, including TGFβRII (the type II receptor for TGFβ). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression.

KLF14 appears to be a master regulator of gene expression in adipose tissue.

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Wikipedia