KIAA1363

NCEH1
Identifiers
Aliases	NCEH1, AADACL1, NCEH, neutral cholesterol ester hydrolase 1
External IDs	MGI: 2443191 HomoloGene: 23251 GeneCards: NCEH1
Gene location (Human) Chr. Chromosome 3 (human) Band 3q26.31 Start 172,630,249 bp End 172,711,218 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band n/a Start 27,182,965 bp End 27,284,608 bp
Gene ontology Molecular function • carboxylic ester hydrolase activity • hydrolase activity • sterol esterase activity • serine hydrolase activity Cellular component • integral component of membrane • endoplasmic reticulum • intracellular membrane-bounded organelle • endoplasmic reticulum membrane • membrane Biological process • lipid catabolic process • metabolic process • lipid metabolic process • catabolic process • xenobiotic metabolic process • low-density lipoprotein particle clearance Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	57552	320024
Ensembl	ENSG00000144959	ENSMUSG00000027698
UniProt	Q6PIU2	Q8BLF1
RefSeq (mRNA)	NM_020792 NM_001146276 NM_001146277 NM_001146278	NM_178772
RefSeq (protein)	NP_001139748 NP_001139749 NP_001139750 NP_065843	NP_848887
Location (UCSC)	Chr 3: 172.63 – 172.71 Mb	Chr 3: 27.18 – 27.28 Mb
PubMed search

57552

320024

ENSG00000144959

ENSMUSG00000027698

Q6PIU2

Q8BLF1

NM_020792
NM_001146276
NM_001146277
NM_001146278

NM_178772

NP_001139748
NP_001139749
NP_001139750
NP_065843

NP_848887

Neutral cholesterol ester hydrolase 1 (NCEH) also known as arylacetamide deacetylase-like 1 (AADACL1) or KIAA1363 is an enzyme that in humans is encoded by the NCEH1 gene.

NCEH is an enzyme located in the endoplasmic reticulum. NCEH hydrolyzes 2-acetyl monoalkylglycerol ether, as part of an enzymatic pathway regulating the levels of platelet activating factor and lysophospholipids that may be involved in cancer development.

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Wikipedia