KHDRBS1

KHDRBS1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2XA6, 3QHE
Identifiers
Aliases	KHDRBS1, Sam68, p62, p68, KH domain containing, RNA binding, signal transduction associated 1, KH RNA binding domain containing, signal transduction associated 1
External IDs	MGI: 893579 HomoloGene: 4781 GeneCards: KHDRBS1
Gene ontology Molecular function • DNA binding • poly(A) binding • poly(U) RNA binding • SH3 domain binding • protein complex binding • protein binding • RNA binding • nucleic acid binding • SH3/SH2 adaptor activity • protein domain specific binding • identical protein binding Cellular component • cytoplasm • Grb2-Sos complex • membrane • nucleus • cytosol • nucleoplasm Biological process • regulation of transcription, DNA-templated • regulation of protein stability • GO:0006350 transcription, DNA-templated • positive regulation of RNA export from nucleus • cell surface receptor signaling pathway • G2/M transition of mitotic cell cycle • regulation of RNA export from nucleus • cell cycle arrest • cell cycle • cell proliferation • negative regulation of transcription, DNA-templated • positive regulation of translational initiation • signal transduction • mRNA processing • positive regulation of signal transduction • regulation of mRNA splicing, via spliceosome • spermatogenesis • protein oligomerization Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10657	20218
Ensembl	ENSG00000121774	ENSMUSG00000028790
UniProt	Q07666	Q60749
RefSeq (mRNA)	NM_001271878 NM_006559	NM_011317
RefSeq (protein)	NP_001258807 NP_006550	NP_035447.3 NP_035447
Location (UCSC)	Chr 1: 32.01 – 32.06 Mb	Chr 4: 129.7 – 129.74 Mb
PubMed search

2XA6, 3QHE

10657

20218

ENSG00000121774

ENSMUSG00000028790

Q07666

Q60749

NM_001271878
NM_006559

NM_011317

NP_001258807
NP_006550

NP_035447.3
NP_035447

KH domain-containing, RNA-binding, signal transduction-associated protein 1 is a protein that in humans is encoded by the KHDRBS1 gene.

This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression.

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Wikipedia