K-Ras

KRAS
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4WA7, 1D8D, 1D8E, 3GFT, 4DSN, 4DSO, 4EPR, 4EPT, 4EPV, 4EPW, 4EPX, 4EPY, 4L8G, 4LDJ, 4LPK, 4LRW, 4LUC, 4LV6, 4LYF, 4LYH, 4LYJ, 4M1O, 4M1S, 4M1T, 4M1W, 4M1Y, 4M21, 4M22, 4NMM, 4OBE, 4PZY, 4PZZ, 4Q01, 4Q02, 4Q03, 4QL3, 4TQ9, 4TQA, 4DST, 4DSU, 5F2E,%%s2MSC, 2MSD, 2MSE
Identifiers
Aliases	KRAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RALD, RASK2, K-ras, KRAS proto-oncogene, GTPase, c-Ki-ras2
External IDs	MGI: 96680 HomoloGene: 37990 GeneCards: KRAS
Gene location (Human) Chr. Chromosome 12 (human) Band No data available Start 25,204,789 bp End 25,250,936 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band No data available Start 145,216,699 bp End 145,250,239 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • nucleotide binding • LRR domain binding • GDP binding • protein complex binding • GTP binding • GMP binding • protein binding • GTPase activity Cellular component • cytoplasm • cytosol • membrane • focal adhesion • extrinsic component of cytoplasmic side of plasma membrane • plasma membrane • mitochondrion • membrane raft Biological process • visual learning • negative regulation of neuron apoptotic process • response to mineralocorticoid • positive regulation of protein phosphorylation • regulation of long-term neuronal synaptic plasticity • regulation of protein stability • epidermal growth factor receptor signaling pathway • positive regulation of MAP kinase activity • cytokine-mediated signaling pathway • negative regulation of cell differentiation • stimulatory C-type lectin receptor signaling pathway • response to glucocorticoid • MAPK cascade • axon guidance • Fc-epsilon receptor signaling pathway • positive regulation of nitric-oxide synthase activity • forebrain astrocyte development • endocrine signaling • positive regulation of NF-kappaB transcription factor activity • homeostasis of number of cells within a tissue • striated muscle cell differentiation • Ras protein signal transduction • epithelial tube branching involved in lung morphogenesis • regulation of synaptic transmission, GABAergic • actin cytoskeleton organization • leukocyte migration • signal transduction • positive regulation of Rac protein signal transduction • positive regulation of gene expression • positive regulation of cell proliferation • ERBB2 signaling pathway • liver development • positive regulation of cellular senescence • female pregnancy • response to isolation stress Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3845	16653
Ensembl	ENSG00000133703	ENSMUSG00000030265
UniProt	P01116	P32883
RefSeq (mRNA)	NM_004985 NM_033360	NM_021284
RefSeq (protein)	NP_004976 NP_203524 NP_004976.2	NP_067259
Location (UCSC)	Chr 12: 25.2 – 25.25 Mb	Chr 12: 145.22 – 145.25 Mb
PubMed search

4WA7, 1D8D, 1D8E, 3GFT, 4DSN, 4DSO, 4EPR, 4EPT, 4EPV, 4EPW, 4EPX, 4EPY, 4L8G, 4LDJ, 4LPK, 4LRW, 4LUC, 4LV6, 4LYF, 4LYH, 4LYJ, 4M1O, 4M1S, 4M1T, 4M1W, 4M1Y, 4M21, 4M22, 4NMM, 4OBE, 4PZY, 4PZZ, 4Q01, 4Q02, 4Q03, 4QL3, 4TQ9, 4TQA, 4DST, 4DSU, 5F2E,%%s2MSC, 2MSD, 2MSE

...
Wikipedia