Juan Hurtado de Mendoza y Guzmán, 3rd Lord and 1st Marquis of Cañete (died 1490) was a Spanish nobleman and military leader.
He was the son of Don Diego Hurtado de Mendoza, 1st Lord of Cañete and of his second wife Teresa de Guzmán. He was elevated to Marquis of Cañete in 1490 by the Catholic Monarchs, who did not know that he had died some days before.