Jean-François Séguier (French pronunciation: [ʒɑ̃ fʁɑ̃swa segje]; 25 November 1703 – 1 September 1784) was a French archaeologist, epigraphist, astronomer and botanist from Nîmes.
He studied law in Montpellier, during which time, he developed a passion for botany. He was a friend and collaborator to Scipio Maffei, with whom he took an extended scientific tour throughout Europe (1732–36). In 1755 he became a member of the Académie de Nîmes, serving as its secrétaire perpétuel from 1765 to 1784. In 1772 he became a member of the Académie royale des Inscriptions et Belles-Lettres.
The plant genus Seguieria (family Petiveriaceae) commemorates his name, as do the botanical species Ranunculus seguieri (Vill., 1779) and Euphorbia seguieriana (Neck., 1770).
His written works include a detailed description of the flora in the vicinity of Verona, titled Plantae Veronenses, seu Stirpium quae in agro Veronensi repriuntur (3 volumes 1745–54). Other noted works associated with Séguier are: