James Tilton (June 1, 1745 – May 14, 1822) was an American physician and soldier from Dover, Delaware. He was a delegate for Delaware in the Continental Congress of 1783 and 1784, and served as Surgeon General of the United States Army during the War of 1812.
James was born in 1745 to Thomas Tilton, a farmer in Kent County, Delaware. After attending an academy in West Nottingham, Pennsylvania, he attended the College of Philadelphia (which was later the University of Pennsylvania). He graduated in 1768 and earned a degree as a Doctor of Medicine in 1771. He started a medical practice at Dover, and also served as an infantry Lieutenant in Dover's Company of the Kent County militia.
When the Revolutionary War began, his militia became part of the 1st Delaware Regiment of the Continental Army. Colonel John Haslet quickly reassigned him to duty as the regimental surgeon. He served with distinction and saw action at the battles of Brooklyn, White Plains, Trenton, and Princeton.
Haslet's unit was virtually destroyed in the Battle of Princeton in January 1777. Colonel Haslet was killed and the command structure was rebuilt. Tilton remained in service with the Continental Army as the head of military hospitals, first at Princeton and later at Trenton, New Jersey and other sites. When active fighting ended in 1781 he returned to his practice at Dover.