JMJD2A

KDM4A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2GF7, 2GFA, 2GP3, 2GP5, 2OQ6, 2OQ7, 2OS2, 2OT7, 2OX0, 2P5B, 2PXJ, 2Q8C, 2Q8D, 2Q8E, 2QQR, 2QQS, 2VD7, 2WWJ, 2YBK, 2YBP, 2YBS, 3NJY, 3PDQ, 3RVH, 3U4S, 4AI9, 4BIS, 4GD4, 4URA, 4V2V, 4V2W, 5D6X, 5F5I, 5A7S, 5F2S, 5A7N, 5A7Q, 5A7O, 5F2W, 5D6W, 5F32, 5FPV, 5A7P, 5A7W, 5F3I, 5A80, 5F37, 5F3E, 5F39, 5F3G, 5F3C, 5D6Y, 5FYC, 5FYI, 5FY8, 5FWE, 5ANQ, 5FYH
Identifiers
Aliases	KDM4A, JHDM3A, JMJD2, JMJD2A, TDRD14A, lysine demethylase 4A
External IDs	MGI: 2446210 HomoloGene: 27780 GeneCards: KDM4A
Gene ontology Molecular function • dioxygenase activity • metal ion binding • methylated histone binding • protein binding • histone demethylase activity (H3-K36 specific) • oxidoreductase activity • ubiquitin protein ligase binding • histone demethylase activity • histone demethylase activity (H3-K9 specific) Cellular component • pericentric heterochromatin • nucleoplasm • fibrillar center • cytoplasm • cytosol • nucleus Biological process • histone demethylation • regulation of transcription, DNA-templated • negative regulation of gene expression • transcription, DNA-templated • cardiac muscle hypertrophy in response to stress • negative regulation of histone H3-K9 trimethylation • viral process • negative regulation of transcription, DNA-templated • negative regulation of autophagy • oxidation-reduction process • negative regulation of cell death • negative regulation of astrocyte differentiation • positive regulation of gene expression • response to nutrient levels • positive regulation of neuron differentiation • covalent chromatin modification • histone H3-K9 demethylation • histone H3-K36 demethylation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9682	230674
Ensembl	ENSG00000066135	ENSMUSG00000033326
UniProt	O75164	Q8BW72
RefSeq (mRNA)	NM_014663	NM_001161823 NM_172382
RefSeq (protein)	NP_055478	NP_001155295.1 NP_759014.2 NP_001155295 NP_759014
Location (UCSC)	Chr 1: 43.65 – 43.71 Mb	Chr 4: 118.14 – 118.18 Mb
PubMed search

2GF7, 2GFA, 2GP3, 2GP5, 2OQ6, 2OQ7, 2OS2, 2OT7, 2OX0, 2P5B, 2PXJ, 2Q8C, 2Q8D, 2Q8E, 2QQR, 2QQS, 2VD7, 2WWJ, 2YBK, 2YBP, 2YBS, 3NJY, 3PDQ, 3RVH, 3U4S, 4AI9, 4BIS, 4GD4, 4URA, 4V2V, 4V2W, 5D6X, 5F5I, 5A7S, 5F2S, 5A7N, 5A7Q, 5A7O, 5F2W, 5D6W, 5F32, 5FPV, 5A7P, 5A7W, 5F3I, 5A80, 5F37, 5F3E, 5F39, 5F3G, 5F3C, 5D6Y, 5FYC, 5FYI, 5FY8, 5FWE, 5ANQ, 5FYH

...
Wikipedia