Ipsapirone

Ipsapirone
Clinical data

Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: uncontrolled
Pharmacokinetic data
Biological half-life	1.3-2.7 hours
Identifiers
IUPAC name 9,9-dioxo-8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]- 9λ⁶-thia-8-azabicyclo[4.3.0]nona-1,3,5-trien-7-one
CAS Number	95847-70-4^Y
PubChem CID	56971
IUPHAR/BPS	42
ChemSpider	51365^Y
UNII	6J9B11MN0K
ChEMBL	CHEMBL8412^Y
Chemical and physical data
Formula	C₁₉H₂₃N₅O₃S
Molar mass	401.484 g/mol
3D model (Jmol)	Interactive image
SMILES O=C2c1ccccc1S(=O)(=O)N2CCCCN4CCN(c3ncccn3)CC4
InChI InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2^Y Key:TZJUVVIWVWFLCD-UHFFFAOYSA-N^Y

Ipsapirone is a selective 5-HT_1A receptor partial agonist of the piperazine and azapirone chemical classes. It has antidepressant and anxiolytic effects. Ipsapirone was studied in several placebo-controlled trials for depression and continues to be used in research.