Iowa 64
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| Maintained by Iowa DOT | ||||
| Length: | 64.355 mi (103.569 km) | |||
| Tourist routes: |
Grant Wood Scenic Byway | |||
| Major junctions | ||||
| West end: |
 US 151 in Anamosa
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| East end: |
  US 52 / IL 64 at Savanna
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Iowa Highway 64 (Iowa 64) is a 64-mile-long (103 km) state highway that runs across two counties in east central Iowa. It begins at an interchange with U.S. Route 151 (US 151) in Anamosa and ends at the Savanna-Sabula Bridge over the Mississippi River near Sabula. It continues through Illinois as Illinois Route 64. The western half of the highway makes up the Grant Wood Scenic Byway.
At one time, Iowa 64 spanned the length of the state. It began at the Missouri River in Council Bluffs where it connected to N-64 in Omaha. It headed northeast and east on highways that today are roughly parallel to Interstate 80 (I-80) and US 30. In 1969, however, Iowa 64 was shortened to its current extent.
Iowa 64 begins at an interchange with US 151 in Anamosa. West of the interchange, the road is County Road E28 (CR E28), which becomes Third Street in Anamosa, while to the east, Iowa 64 begins its eastward trek. It leaves Anamosa heading to the south-southeast. After an S curve that takes the road to the south and then back east, the highway passes Antioch School, which Iowa painter Grant Wood attended for four years. The highway rises
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