*** Welcome to piglix ***

Iohexol

Iohexol
Iohexol.svg
Clinical data
Trade names Omnipaque, others
AHFS/Drugs.com Micromedex Detailed Consumer Information
Pregnancy
category
  • US: B (No risk in non-human studies)
Routes of
administration
intrathecal, intravascular, by mouth, intracavital, rectal
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding Low
Metabolism Nil
Biological half-life Variable
Excretion Kidney, unchanged
Identifiers
Synonyms 5-[N-(2,3-Dihydroxypropyl)acetamido]-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard 100.060.130
Chemical and physical data
Formula C19H26I3N3O9
Molar mass 821.138 g/mol
3D model (Jmol)
 NYesY (what is this?)  

Iohexol, sold under the trade names Omnipaque among others, is a contrast agent used during X-rays. This includes when visualizing arteries, veins, ventricles of the brain, the urinary system, and joints, as well as during computer tomography (CT scan). It is given by mouth, injection into a vein, or into a body cavity.

Side effects include vomiting, skin flushing, headache, itchiness, kidney problems, and low blood pressure. Less commonly allergic reactions or seizures may occur. It should not be used by those who have a iodine allergy. Use in the later part of pregnancy may cause hypothyroidism in the baby. Iohexol is an iodinated non-ionic radiocontrast agent. It is in the low osmolar family.

Iohexol was approved for medical use in 1985. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 10.99 USD per 50 ml vial. In the United States a dose costs 50 to 100 USD.


...
Wikipedia

...